Completed Projects

PUBLISHED PACT APPROVED CLINiCAL TRIALS:

1. Turgeon AF, et.al. Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury. N Engl J Med. 2024 Aug 22;391(8):722-735. Funding CIHR
2. Deschamps A, et.al. Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery: The ENGAGES-Canada Randomized Clinical Trial. JAMA 2024;332;(2):112-123. doi:10.1001/jama.2024.8144. Funding CIHR
3. Spence J, et.al. . Benzodiazepine-Free Cardiac Anesthesia for Reduction of Postoperative Delirium: A Cluster Randomized Crossover Trial. JAMA Surg. 2025 Mar 1;160(3):286-294. Funding CIHR
4. McIsaac DI et al Home-Based Pre-habilitation in Older Surgical Patients with Frailty: A randomized Trial JAMA Surg. doi:10.1001/jamasurg.2025.5288. Funding CIHR
5. Wijeysundera, DN et al Significant new disability after major non-cardiac surgery in older adults aged 65 years and older in Canada: a multicentre prospective cohort study Lancet Healthy Longev 2025; 6: 100789. Funding CIHR